Brain Tumours: Teenagers and Young Adults

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Introduction to the Brain

The brain and the spinal cord make up the central nervous system (CNS), which controls and coordinates most bodily functions. The brain, often referred to as the “control center,” is encased within the skull, providing a protective structure. The spinal cord, composed of a bundle of nerves, extends down the back and acts as a relay for messages between the brain and other parts of the body.

The brain and spinal cord are protected by three thin layers of tissue known as the meninges. Between two of these layers is cerebrospinal fluid (CSF), which further cushions and protects the CNS.

Main Parts of the Brain

  1. Cerebrum: This is the largest part of the brain, located at the top of the head, and is made up of two halves, known as hemispheres. It plays a key role in:
    • Thinking, learning, and memory
    • Problem-solving and emotions
    • Sensory perception (e.g., touch)
    • Awareness of body position
  2. Cerebellum: Found at the back of the head, near the middle, it controls:
    • Movement and balance
    • Coordination of muscles
  3. Brain Stem: This part connects the brain to the spinal cord and is located at the lower end of the brain, just above the back of the neck. It regulates automatic functions such as:
    • Breathing
    • Heartbeat
    • Blood pressure
    • Eye movements and swallowing
  4. Pituitary Gland: Situated in the middle of the brain, it is responsible for producing hormones that regulate:
    • Growth
    • Metabolism
    • Menstrual cycles in females
    • Sperm production in males

Types of Brain Tumors

Brain tumors can be classified as either benign (non-cancerous) or malignant (cancerous). These tumors are often named based on the type of cells they originate from. Brain tumors can also be categorized as:

  • Primary Tumors: Originating within the brain itself.
  • Secondary Tumors: Spread to the brain from cancer in another part of the body.
Benign Brain Tumors
  • Generally grow slowly and press on surrounding brain tissue but rarely invade it.
  • Less likely to spread to other parts of the brain or spinal cord.
  • Can often be removed surgically; however, if located in a complex area, additional treatments like radiotherapy or chemotherapy may be necessary.
Malignant Brain Tumors
  • Often spread from where they began to nearby brain tissue.
  • More likely to cause symptoms due to increased pressure inside the skull.
  • Can sometimes spread through the CSF to other areas of the brain or spinal cord.

Common Brain Tumors in Teenagers and Young Adults

  1. Pituitary Tumors:
    • Usually benign.
    • Commonly categorized as pituitary adenomas or craniopharyngiomas.
    • May cause hormonal imbalances.
  2. Gliomas:
    • Develop from glial cells (supporting cells of the CNS).
    • Common types include astrocytomas, oligodendrogliomas, and ependymomas.
    • Astrocytomas and oligodendrogliomas are among the most frequently diagnosed. They are classified by their growth rate, ranging from low to high grade.
  3. Medulloblastomas:
    • Typically start in the cerebellum.
    • Can spread via CSF to other brain or spinal cord areas.
  4. Germ Cell Tumors:
    • Rare tumors originating from germ cells, which can develop into various tissue types.
    • Germ cell tumors in the brain can be benign or malignant and may have counterparts in the ovaries or testicles.

Symptoms of Brain Tumors

Symptoms depend on the tumor’s size, location, and how it affects the brain’s function. Common symptoms include:

  • Persistent headaches
  • Nausea and vomiting, particularly in the morning
  • Seizures (fits)
  • Behavioral or cognitive changes, such as personality shifts or memory issues
  • Vision problems (e.g., blurred vision)
  • Weakness or paralysis on one side of the body
  • Balance and coordination difficulties

Diagnosis and Tests

  • Neurological Examination: Assessment of sensory and motor function.
  • Imaging Tests:
    • MRI (Magnetic Resonance Imaging): Provides detailed brain scans.
    • CT (Computed Tomography) Scan: Quick imaging test often used as a preliminary scan.
  • Biopsy: Removal and examination of tumor tissue.
  • Blood Tests: To rule out other conditions and assess health before procedures.

Treatment Options

  1. Surgery: Removing as much of the tumor as possible.
  2. Radiotherapy: High-energy beams to kill or slow the growth of tumor cells.
  3. Chemotherapy: Drugs targeting cancer cells.

Emotional Support and Guidance

Dealing with a brain tumor diagnosis is challenging. Support is available from healthcare professionals, counseling services, and peer support groups, helping patients and families navigate emotional and medical hurdles.

Symptoms of Brain Tumors

Overview

The symptoms of a brain tumor vary based on its size, type, and location in the brain. Tumors can:

  • Cause fits (seizures).
  • Affect brain functions by interfering with the messages sent from one part of the brain to another.
  • Create raised intracranial pressure due to the limited space within the skull, which leads to increased pressure around the brain as the tumor grows.

Common Symptoms of Raised Intracranial Pressure

  • Headaches: Typically more severe in the morning and may be accompanied by nausea.
  • Vomiting or Nausea: Usually occurring in the morning.
  • Fits (Seizures): Sudden and uncontrolled electrical disturbances in the brain.
  • Irritability or Loss of Interest: A sudden disinterest in day-to-day activities, friends, school, or hobbies.
  • Vision Problems: Blurred or double vision.
  • Drowsiness or Sleepiness: An increase in the need to sleep or frequent drowsiness.
  • Balance and Coordination Issues: Difficulty walking or balancing; may also include weakness on one side of the body.
  • Speech Difficulties: Trouble finding words, forming sentences, or maintaining a conversation.
  • Personality or Behavioral Changes: Shifts in mood, personality, or behavior that seem unusual for the individual.

Importance of Early Detection

It is essential to remember that these symptoms often have simple and less serious explanations. However, if you notice any of these signs or feel concerned, it is crucial to speak with your GP (General Practitioner) as soon as possible. They can assess your symptoms, arrange tests if necessary, and refer you to a specialist if needed.

Causes of Brain Tumors

Unknown Origins

The exact cause of most brain tumors is not well understood. Researchers continue to investigate potential risk factors, but in most cases, there is no known trigger.

Genetic Factors

Certain rare genetic conditions can increase the risk of developing a brain tumor. Examples include:

  • Neurofibromatosis type 1 (NF1)
  • Neurofibromatosis type 2 (NF2)

These conditions may run in families and raise the likelihood of developing a tumor due to inherited genetic mutations.

Environmental Factors and Myths

Various environmental factors have been suggested as potential causes of brain tumors, including:

  • Mobile Phones: Despite extensive research, no strong evidence has been found to support a link between mobile phone usage and brain tumors.
  • Power Lines: Similar to mobile phones, there is no conclusive evidence to suggest power lines are a cause.
  • Viruses: Some studies have explored the role of certain viruses, but strong evidence remains lacking.

It is important to emphasize that nothing you have done or failed to do has caused a brain tumor.

Seeking Support and Diagnosis

If you or someone you know experiences any symptoms of a brain tumor, it is vital to reach out to a GP. They can provide guidance, perform preliminary assessments, and, if necessary, refer you to a specialist doctor for further evaluation and testing.

Additional Resources

If you would like more information, consider exploring these areas:

  • Tests for Brain Tumors: Detailed information on the diagnostic process.
  • Treatment Options for Brain Tumors: Insights into different treatment methods.
  • Understanding the Brain: Information about the structure and function of the brain.

For more comprehensive details, including brain tumors in children and general brain tumor information, you may also wish to visit reputable medical websites or consult healthcare professionals.

Having tests for brain tumours

Seeing Your GP

When you visit your GP (General Practitioner), they will conduct a basic examination and discuss your symptoms. Depending on what they find:

  • They may order tests.
  • They might refer you to the hospital to see a specialist right away. Specialists for brain-related issues are called neurologists (doctors who diagnose and treat brain and nervous system disorders) or neurosurgeons (doctors who perform surgeries on the brain and spinal cord).

Emergency Situations: Sometimes, brain tumors are diagnosed in emergency situations, such as if someone has a sudden seizure (fit) and is taken to the hospital.

At the Hospital

At the hospital, you will usually be seen by specialists at a center that focuses on brain tumors. Your specialist will:

  • Ask about your symptoms and how you have been feeling.
  • Use an instrument with a light (like an ophthalmoscope) to examine the back of your eyes. This is to check for swelling, which can indicate raised pressure in your head.

Physical Checks: The specialist may also examine:

  • Your balance and coordination.
  • Your muscle strength.
  • Your reflexes.
  • How you respond to pinpricks on your skin.
  • Your eyesight and hearing might also be tested.

Tests You Might Have

The tests are necessary to confirm a diagnosis and help your doctors decide on the best treatment. Your doctor and specialist nurse will explain these tests in detail, but don’t hesitate to ask questions if you’re unsure.

Common Tests Include:

  1. CT Scan or MRI Scan:

    • CT Scan (Computerized Tomography): Provides detailed X-ray images of your head.
    • MRI Scan (Magnetic Resonance Imaging): Uses magnetic fields to create highly detailed images of your brain.
  2. Blood Tests:

    • These help assess your general health and may measure specific hormones or chemicals in your blood.
  3. Lumbar Puncture:

    • A small needle is used to collect fluid from the base of your spine. This test checks for cancer cells in the cerebrospinal fluid (CSF), which surrounds the brain and spinal cord.
  4. X-Rays:

    • X-rays may be taken of your skull and chest, depending on what your doctors need to see.

Having a Biopsy

A biopsy involves removing a small sample of the tumor to determine the exact type of cells involved. This is crucial for planning the most effective treatment.

  • The biopsy is done under general anaesthetic (you’ll be in a deep sleep during the procedure).
  • The MRI or CT scan is used to locate the exact position of the tumor.
  • A small hole is made in the skull, and a fine needle is passed through to collect a sample.

Guided Biopsy:

  • In some cases, a head frame is used to guide the surgeon precisely to the right spot. This is called a stereotactic biopsy.

Waiting for Results

Waiting for test results can be stressful and frightening. Remember, you don’t have to go through it alone. Talking about your worries with family, friends, your specialist nurse, or your doctor can provide comfort. You can also reach out to organizations like Macmillan Cancer Support for additional help.

Additional Resources

For more detailed information, you might want to explore these related areas:

  • Symptoms of Brain Tumors
  • Treatment Options for Brain Tumors
  • Understanding the Brain and How it Works

If you need information on brain tumors affecting all ages or on children specifically, there are general and pediatric resources available too.

Treatment Planning

A specialized team of doctors will discuss and plan your treatment, which often involves multiple therapies. You might see:

  • Neurosurgeon: Specializes in brain surgeries.
  • Neurologist: Treats brain-related conditions.
  • Oncologist: Treats tumors using radiotherapy and chemotherapy.

Your care team may also include a specialist nurse who supports teenagers and young adults with cancer, or someone who specializes in brain conditions. Radiographers administer radiotherapy if it is part of your treatment.

The specific treatment depends on:

  • The type of brain tumor.
  • Its size and location.

Main Treatments for Brain Tumors

  1. Surgery:

    • The goal is to remove as much of the tumor as possible.
    • Your surgeon will discuss what’s involved, including benefits and risks.
    • Awake Craniotomy: For some low-grade gliomas, you may remain awake for part of the surgery. Don’t worry; you’ll receive medication to stay comfortable.

    After Surgery:

    • Close monitoring for 12-24 hours, often using a ventilator temporarily.
    • Bandages and drainage tubes around the head may be present to manage fluids and blood.
    • Pain management is provided, and swelling/bruising around the eyes and face should subside within days.
  2. Radiotherapy:

    • Uses high-energy X-rays to target cancer cells.
    • Commonly used after surgery, if surgery is not possible, or if a tumor returns.
    • Types include photon radiotherapy, proton radiotherapy, and stereotactic radiosurgery/radiotherapy.
    • Side Effects: Hair loss, skin changes, tiredness, nausea, headaches, and potential late effects (e.g., memory or concentration issues). Your doctors will guide you through managing these.
  3. Chemotherapy:

    • Uses drugs to destroy cancer cells.
    • May be given before or after surgery, alongside radiotherapy, or when a tumor returns.
    • Side Effects: Risk of infection, tiredness, nausea, hair loss, potential fertility issues. Your team will provide support to manage these effects.

Supportive Medications

  • Steroids: Help reduce swelling around the tumor.
    • Side Effects: Temporary weight gain, mood changes, indigestion, higher infection risk, changes in blood sugar levels.
  • Anticonvulsants: Prevent seizures if the tumor affects certain areas of the brain.

Coping and Support

  • You’ll have follow-up appointments to monitor your health and manage any long-term effects.
  • Discuss your treatment plan with your doctors, ask questions, and take time to talk it over with your family.

Additional Resources:

  • More information about symptoms of brain tumors, having tests, and understanding the brain is available.
  • If you’re seeking information for all age groups, general brain tumor resources can be useful.

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